Rates of HIV-1 superinfection and primary HIV-1 infection are similar in female sex workers in Uganda.

Correlates of HIV-Related Self-stigma Among Female Sex Workers in Malaysia

Background: Not much is known about correlates of HIV-related self-stigma among female sex workers. Using the theory of planned behavior in the Malaysian context, this study investigated the relationships of HIV knowledge, attitudes towards HIV, attitudes towards people living with HIV, perceived social support, self-esteem, and age with HIV-related self-stigma, also how much of the variance in...

Incidence of HIV-1 dual infection and its association with increased viral load set point in a cohort of HIV-1 subtype C-infected female sex workers.

This longitudinal study aimed to determine the incidence and pathogenic implications of dual human immunodeficiency virus type 1 (HIV-1) infection in a cohort of female sex workers. Blood samples from 31 recently infected women were screened by use of a heteroduplex mobility assay and sequencing. The median viral load set point was 5404 copies/mL (n=22), which was measured by use of the bDNA as...

Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States.

BACKGROUND Human immunodeficiency virus type 1 (HIV-1) dual infection (DI) has been associated with decreased CD4 T-cell counts and increased viral loads; however, the frequency of intrasubtype DI is poorly understood. We used ultradeep sequencing (UDS) to estimate the frequency of DI in a primary infection cohort of predominantly men who have sex with men (MSM). METHODS  HIV-1 genomes from l...

The Impact of Drug and Alcohol Consumption and Socio-demographic Variables on the Age of First Selling Sex among Iranian Female Sex Workers

Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda, by use of next-generation deep sequencing.

HIV superinfection, which occurs when a previously infected individual acquires a new distinct HIV strain, has been described in a number of populations. Previous methods to detect superinfection have involved a combination of labor-intensive assays with various rates of success. We designed and tested a next-generation sequencing (NGS) protocol to identify HIV superinfection by targeting two r...